Best Hangover Prevention Supplements [Top of 2023]

Learn what to look for and what to avoid when shopping for a hangover prevention supplement.

Are you looking for the best hangover prevention supplement so that you don’t regret your nights out? These supplement rankings are for you.

Hangovers are without a doubt one of the worst things that we voluntarily subject ourselves to – but luckily, modern science has led to the discovery of a variety of different hangover prevention remedies that can help.

It can be difficult to choose the best hangover prevention supplement. Finding the best supplement depends on personal preferences method of ingestion, flavor, and price – as well as factors such as the safety of the manufacturer’s processes and ingredients. Familiarizing yourself with the facts about sleep supplements and potential safety concerns will allow you to confidently select the best hangover prevention supplement.

To make it easy for you, we have researched and compiled a list of the best hangover powders and hangover pills on the market. These supplements will help replenish nourishments and balance your electrolyte levels while drinking alcohol.

At Health Rankings, we analyzed dozens of clinical studies on hangover supplements and the science of hangovers while creating this guide. You’ll learn what ingredients work and which ones to avoid along with our top picks for 2023.

Best Hangover Prevention Supplements of 2023

#1 Best Overall: PREGAME by Vitaliboost

Review of PREGAME hangover prevention supplement

4.9/5

MULTI-SOURCE REVIEW SCORE

A+

OVERALL RATING

PROS

  • Great price ($1.66/serving)
  • Safety: NSF Certified, Tested by a 3rd Party Lab
  • Good mix of ingredients: Vitamin B12, Magnesium, Potassium, Sodium, and extracts from Acerola, Beet Root, and Coconut Water
  • 60-day risk-free, money-back, product guarantee

CONS

  • Exclusively sold online
  • Free shipping only for orders over $50
THE BOTTOM LINE

PREGAME is the best hangover prevention supplement on the market. Its ingredients are each backed by multitudes of studies about hangovers, hydration, and electrolyte balance in the body. This is the best all-around formula that we’ve found when it comes to supplements to prevent hangovers.

This was the only product that we found on the market that’s NSF certified and third-party tested. It also has no hidden additives and ingredient dosages are not hidden behind a proprietary blend.

Additionally, their return policy was one of the best we’ve come across: a comprehensive 60-day, no questions asked money-back guarantee.

#2: H-Proof by Kaplan

Review of H-Proof hangover prevention supplement powder

4.6/5

MULTI-SOURCE REVIEW SCORE

B+

OVERALL RATING

PROS

  • Contains Vitamin B12, Magnesium, and Potassium

CONS

  • More expensive than similar supplements ($88.50 for 30 servings, or $2.95/serving)
  • Contains some ingredients that are likely unnecessary to prevent hangovers
  • Contains a proprietary blend
THE BOTTOM LINE

H-Proof is our second favorite hangover prevention supplement on the market. Its ingredients include Vitamin B12, Magnesium, and Potassium which each have strong scientific backing.

However, H-Proof also contains two things that we don’t like: unnecessary ingredients, and a proprietary blend. There are several ingredients that seem unnecessary, and there is no way to know exactly what dose you’re getting from their proprietary blend.

The refund policy is good at 30 days.

#3: ZBiotic Drink

Review of zbiotic hangover prevention drink

4.6/5

MULTI-SOURCE REVIEW SCORE

B+

OVERALL RATING

PROS

  • Unique prebiotic blend
  • Contains potassium & sodium

CONS

  • Most expensive option on the market in this space ($270 for 30 servings, or $9/serving)
  • Missing ingredients like magnesium and some electrolytes that we’d prefer to see
THE BOTTOM LINE

ZBiotic contains a unique probiotic blend designed to help you digest alcohol in a more healthy way. We love its unique approach to hangover prevention. We also like that it contains Sodium and Potassium.

However, ZBiotic is missing a few ingredients that we’d like to see such as magnesium and certain natural electrolytes.

ZBiotic offers a money-back guarantee – and we’d hope so given that this is almost 10x more expensive per serving than even the priciest competitors!

Avoid: Over EZ by EZ Lifestyle

Review of Over EZ hangover supplement

3.5/5

TOTAL RANKING

C

OVERALL RATING

PROS

  • Not many to speak of. We do not recommend this supplement for a variety of reasons.

CONS

  • More expensive than similar supplements ($83.29 for 30 servings, or $2.92/serving)
  • Contains some ingredients that are likely unnecessary to prevent hangovers
  • Contains a proprietary blend
THE BOTTOM LINE

Over EZ is a supplement marketed by the tagline “TikTok made me buy it” – however, we do not recommend buying this.

Over EZ raises a few red flags for us: first of all, it was almost impossible to find the ingredients that it contained before we ordered it for testing. Next, we found that it contains a proprietary blend. There is no way to know exactly what dose you’re getting from their proprietary blend.

We were unable to find information about NSF certification, GMP certification, 3rd-party lab testing, and other areas that we typically evaluate for safety.

Final Checklist – What to Look For

Now that you know what ingredients to look for and what to avoid, it’s also important to keep these additional tips in mind when looking for sleep boosting gummmies.

Clinically Recommended Dosages

Some brands will use quality ingredients, but skimp out on dosages in order to save money. So even if you’re getting the right ingredients, if they’re not in their recommended dosages, you won’t experience the full benefits.

Money-Back Guarantee

It’s always a good idea to invest in a supplement that offers a money-back guarantee that shows the company’s faith in its product. Look for brands that offer at least a 60-day money-back guarantee.

Final Checklist – What to Avoid

Supplements that claim to cure hangovers after-the-fact

The unfortunate truth is that you can’t cure a hangover. Supplements that claim to be a miracle-morning-after-cure simply do not work. The only thing that you can do to get rid of a hangover is wait. Based on our research, we recommend supplements focused on hangover prevention.

*Results are based on our proprietary ranking system and do not necessarily reflect typical results from the use of these products. We review as many products as we can, but we are not able to review every supplement on the market. Please visit product websites for more information.